despair:1

noun
de*spair \ di-ˈsper \
14th century{ds||1||}
  • utter loss of hope
  • a cause of hopelessness

despair:2

verb
despair \
14th century{ds|i|||}
  • to lose all hope or confidence
  • to lose hope for

self-despair

noun
self-de*spair \ ˌself-di-ˈsper \
1652
  • despair of oneself : hopelessness
Powered by Merriam-Webster